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Table 2 Relationship between dietary interventions (hemin and fat) and outcome variables in A/J Min/+ mice

From: Colorectal Carcinogenesis in the A/J Min/+ Mouse Model is Inhibited by Hemin, Independently of Dietary Fat Content and Fecal Lipid Peroxidation Rate

   Hemin+ vs. Hemin High fat vs. low fat
   Coefficient p-value Coefficient p-value
Colon
Flat ACF Number per animal −13.0 [−25.1– −0.9] 0.036 5.0 [−7.2–17.2] 0.421
Average Size −0.000 [−0.003–0.002] 0.862 0.002 [−0.001–0.004] 0.142
Load −0.18 [−0.35– −0.01] 0.040 0.14 [−0.03–0.31] 0.105
Tumor Number per animal −1.0 [−4.0–2.0] 0.513 1.0 [−2.0─4.0] 0.515
Average Size −0.28 [−0.67–0.13] 0.181 0.66 [0.23–1.07] 0.002
Load −0.55 [−3.60–2.50] 0.723 1.39 [−1.69–4.46] 0.377
Small intestine
Tumor Number per animal 2.0 [−5.2–9.2] 0.588 6.0 [−1.3–13.3] 0.107
Average Size 0.00 [−0.06–0.58] 1.000 0.12 [0.07–0.18] <0.001
Load 1.13 [−2.52–4.78] 0.544 5.54 [1.86–9.21] 0.031
Fecal Parameters
  TBARS 7.1 [3.8–10.4] <0.001 5.3 [1.9–8.6] 0.002
  Fecal water content 4.5 [1.9–7.0] 0.001 −2.7 [−5.2– −0.1] 0.045
  1. Regression coefficients [95 % confidence interval] from quantile regression are presented. Significant results (p < 0.05) are shown in bold text