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Fig. 3 | BMC Cancer

Fig. 3

From: The differential role of HTRA1 in HPV-positive and HPV-negative cervical cell line proliferation

Fig. 3

Effect of HTRA1 on apoptosis. Apoptosis in the CasKi (a) and C33 (b) cell lines was analyzed by flow cytometry after transfection and 14 days of G418 selection. No difference in apoptosis was observed in either cell line between cells overexpressing HTRA1 and those with low HTRA1 expression levels (p > 0.05). Viable cells are located in the bottom left (FITC-Annexin V negative/PI negative), early apoptotic cells in the bottom right (FITC-Annexin V positive/PI negative), late apoptotic or necrotic cells in the top right (FITC-Annexin V positive/PI positive) and necrotic cells in the top left quadrants (FITC-Annexin V negative/PI positive)

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