Table 1 Summary of the suggestive risk factor for poor prognosis in MEC
High risk | |
Histological findings: Spindle cell type [3] | |
IHC for p53, p63 is positive, Ki67 labeling index is high [1, 3, 5] | |
Clinical stage, size, extensive invasion into the surrounding tissue, perineural invasion [2, 12, 19] | |
Low risk | |
Site of origin: a minor salivary gland [17] | |
Histological findings: Clear cell component [20] | |
Unknown or Equivalent or controversial | |