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Table 1 Expression levels of the three LPARs in ovarian cancer cell lines

From: LPA receptor 1 mediates LPA-induced ovarian cancer metastasis: an in vitro and in vivo study

 

LPAR1

LPAR2

LPAR3

mRNA expression

P value

mRNA expression

P value

mRNA expression

P value

Invasive ovarian cancer cells

 ES2

1.591 ± 0.033

 

0.075 ± 0.031

 

0.702 ± 0.047

 

 OVCAR429

2.235 ± 0.014

 

1.602 ± 0.012

 

0.086 ± 0.071

 

 HEY

0.770 ± 0.038

 

0.005 ± 0.063

 

0.261 ± 0.032

 

 OVCAR433

1.919 ± 0.013

 

0.847 ± 0.085

 

0.064 ± 0.044

 

 OVCAR5

0.715 ± 0.012

 

0.140 ± 0.033

 

0.005 ± 0.017

 

 SKOV3

0.633 ± 0.078

 

0.087 ± 0.087

 

0.177 ± 0.105

 

 OCC1

1.165 ± 0.014

 

0.138 ± 0.011

 

2.751 ± 0.037

 

Non-invasive ovarian cancer cells

 

0.003*

 

0.246

 

0.804

 OVCAR3

0.252 ± 0.011

 

0.192 ± 0.021

 

0.451 ± 0.022

 

 HEC1A

0.002 ± 0.025

 

0.053 ± 0.045

 

0.001 ± 0.065

 

 IGROV1

0.383 ± 0.045

 

0.129 ± 0.015

 

0.082 ± 0.045

 

 TOV21G

0.274 ± 0.024

 

0.002 ± 0.024

 

0.026 ± 0.008

 

 A2780

0.007 ± 0.014

 

0.081 ± 0.033

 

2.070 ± 0.102

 

 OVCAR4

0.001 ± 0.013

 

0.268 ± 0.008

 

0.067 ± 0.073

 
  1. * P < 0.003 indicates statistically significant difference