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Table 2 Endothelial gene signatures in TCGA cancer sets

From: The expression pattern of matrix-producing tumor stroma is of prognostic importance in breast cancer

BRCA COAD COAD cont HNSC KIRC KIRC cont LUAD LUSC
ARHGEF15 ARHGEF15 MMRN2 CD34 ARHGEF15 LDB2 ARHGEF15 CD93
CD34 BCL6B MYCT1 CDH5 BCL6B MMRN2 CD34 CDH5
CDH5 CALCRL PCDH12 CXorf36 CD34 MYCT1 CDH5 CXorf36
CXorf36 CD34 RHOJ ELTD1 CDH5 NOTCH4 CXorf36 TIE1
ELTD1 CD93 S1PR1 ESAM CLEC14A PCDH12 TIE1  
ERG CDH5 SH2D3C RHOJ CXorf36 PLVAP   
ESAM CLEC14A SHE TIE1 DLL4 ROBO4   
LDB2 CXorf36 TEK   ECSCR S1PR1   
MMRN2 ELTD1 TIE1   ELTD1 TIE1   
MYCT1 ERG    ERG    
TIE1 GPR116    ESAM    
  LDB2    GPR4    
  1. The signatures were defined by an iterative process. Starting with the expanded endothelial gene set (Additional file 10: Table S5) the gene with the lowest mean value of the correlation coefficients of the log2 expression with the genes in the set was removed from the set. The process was reiterated until all genes had a mean correlation coefficient above 0.85