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Fig. 4 | BMC Cancer

Fig. 4

From: miR-124-3p functions as a tumor suppressor in breast cancer by targeting CBL

Fig. 4

Effects of miR-124-3p and CBL on the proliferation and invasion of MCF-7 cells. ac CCK8 analysis of the proliferation rate of MCF-7 cells treated with control siRNA or CBL siRNA (a), with control plasmid or CBL plasmid (b), or with one of the combinations: control mimic plus control plasmid, miR-124-3p mimic plus control plasmid, control mimic plus CBL plasmid, or miR-124-3p mimic plus CBL plasmid (c). dg Transwell analysis of invaded MCF-7 cells treated with control siRNA or CBL siRNA (d), with control plasmid or CBL plasmid (d), or with one of the combinations: control mimic plus control plasmid, miR-124-3p mimic plus control plasmid, control mimic plus CBL plasmid, or miR-124-3p mimic plus CBL plasmid (e). d and e representative images; f and g quantitative analysis. *P < 0.05; **P < 0.01; ***P < 0.001

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