Oral perfluorooctane sulfonate (PFOS) lessens tumor development in the APCmin mouse model of spontaneous familial adenomatous polyposis

Table 1 Depicts the gender, dose groups, animal numbers and duration of exposure for the animals completing each study

Trial	Dose Groups in mg/kg (N)	Age at First Exposure	Treatment Duration	Age at Tumor Counts
Females	0 (8), 20 (7^a), 250 (4^b)	7 weeks	8 weeks	15 weeks
Males	0 (6), 10 (6), 50 (6), 200 (6)	6 weeks	9 weeks	15 weeks

^aOne animal developed breast cancer and was dropped from study; ^bfour animals had > 10% weight loss before 15 weeks and were lost to follow-up. “0” dose animals received vehicle only

ISSN: 1471-2407