|
Variable
|
Valid cases
|
MLPA data
|
p-value
|
|---|
| |
(n)
|
BRCA1-like
|
Non-BRCA1-like
| |
|---|
|
Total
|
144
|
63
|
81
| |
|
Age
|
143
| | |
0.265
|
|
<50
|
54
|
27
|
27
| |
|
≥50
|
89
|
36
|
53
| |
|
Tumor size
|
143
| | |
0.979
|
|
pT 1
|
54
|
24
|
30
| |
|
pT 2
|
69
|
31
|
38
| |
|
pT 3
|
8
|
3
|
5
| |
|
pT 4
|
12
|
5
|
7
| |
|
Nodal status
|
141
| | |
0.145
|
|
Negative
|
71
|
35
|
36
| |
|
Positive
|
70
|
26
|
44
| |
|
Histological grade
|
139
| | |
0.0004*
|
|
1
|
6
|
0
|
6
| |
|
2
|
28
|
5
|
23
| |
|
3
|
105
|
57
|
48
| |
|
Histology
|
144
| | |
0.062
|
|
Invasive-ductal
|
113
|
53
|
60
| |
|
Invasive-medullary
|
11
|
6
|
5
| |
|
Other
|
20
|
4
|
16
| |
|
Adjuvant chemotherapy
|
142
| | |
0.044*
|
|
None
|
34
|
10
|
24
| |
|
Yes
|
108
|
53
|
55
| |
|
Radiation therapy
|
142
| | |
0.017*
|
|
None
|
23
|
5
|
18
| |
|
Yes
|
119
|
58
|
61
| |
- BRCA1-like classification with cut-off value ≥ 0.5, non-BRCA1-like classification with cut-off value < 0.5
- *statistically significant with chi square test
