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Table 2 Sensitivity of the MLPA test

From: Identification of BRCA1-like triple-negative breast cancers by quantitative multiplex-ligation-dependent probe amplification (MLPA) analysis of BRCA1-associated chromosomal regions: a validation study

  BRCA1 mutation BRCA1 methylation BRCA1 mutation/methylation
Total 18 22 40
BRCA1-like (≥0.5) 15 20 35
False negative 3 2 5
Sensitivity (%) 83 91 87.5
  1. BRCA1-like classification with cut-off value ≥ 0.5, non-BRCA1-like classification with cut-off value < 0.5