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Table 2 Sensitivity of the MLPA test

From: Identification of BRCA1-like triple-negative breast cancers by quantitative multiplex-ligation-dependent probe amplification (MLPA) analysis of BRCA1-associated chromosomal regions: a validation study

 

BRCA1 mutation

BRCA1 methylation

BRCA1 mutation/methylation

Total

18

22

40

BRCA1-like (≥0.5)

15

20

35

False negative

3

2

5

Sensitivity (%)

83

91

87.5

  1. BRCA1-like classification with cut-off value ≥ 0.5, non-BRCA1-like classification with cut-off value < 0.5
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BMC Cancer

ISSN: 1471-2407

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