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Table 1 Collected data throughout the REFRACT-LYMA cohort study

From: The REFRACT-LYMA cohort study: a French observational prospective cohort study of patients with mantle cell lymphoma

Collected data

Reason for follow-up

Baseline visit

Monitoring without treatment

Monitoring with treatment

Disease progression

Disease Relapse

New treatment

Treatment toxicity

End of treatment

Sociodemographic data

 Age

X

       

 Sex

X

       

 Education

X

       

 Professiona

X

       

 Living situationa

X

       

 Place of residencea

X

       

 Ethnicity

X

       

 Number of childrena

X

       

 Death informationa

        

Epidemiological data

 Body weight and heighta

X

       

 Physical activitiesa

X

       

 Smoking and alcohol habitsa

X

       

 Family history of cancer

X

       

 Personal history of lymphoma

X

       

 Constitutive or acquired immunodeficiency

X

       

Medical data

 ECOG performance status

X

X

X

X

X

X

X

X

 Disease status

X

X

X

X

X

X

X

X

 Ann Arbor staging

X

 

X

X

X

X

  

 IPI

X

 

X

X

X

X

  

 MIPI

X

 

X

X

X

X

  

 Splenomegaly

X

 

X

X

X

X

  

 Digestive expression of lymphoma

X

 

X

X

X

X

  

 Circulating tumor cells

X

 

X

X

X

X

  

 Number of extranodal territories

X

 

X

X

X

X

  

 Serum lactate dehydrogenase level

X

 

X

X

X

X

  

 Creatinine level

X

 

X

X

X

X

  

 Hemoglobin concentration

X

 

X

X

X

X

  

 White blood cell count

X

 

X

X

X

X

  

 Bone marrow biopsy data

X

 

X

X

X

X

  

 Tumor cell cytological morphology

X

 

X

X

X

X

  

 Molecular markers

X

 

X

X

X

X

  

 Genetic abnormality: t(11,14) and del17

X

 

X

X

X

X

  

 B-cell and MCL markers

X

 

X

X

X

X

  

 Monoclonality

X

 

X

X

X

X

  

 MRD

X

X

X

X

X

X

  

 PET data

X

 

X

X

X

X

  

 Adverse events

X

X

X

X

X

X

X

X

Treatment data

 Treatment characteristics

X

 

X

X

X

X

 

X

Comorbidity

 CIRS-Ga

X

       

 Quality of life

X

X

X

X

X

X

X

X

Biological samples and functional assays

 Biological samples: blood sample, bone marrow, lymph node, pleural effusion, cerebrospinal fluid

X

 

X

X

X

X

X

 

 Flow cytometry

X

 

X

X

X

X

X

 

 RNA analysis:

X

 

X

X

X

X

X

 

 Functional assays

X

 

X

X

X

X

X

 
  1. aData updated every year