Table 3 Multivariable Cox proportional hazards regression analysis
From: Oral cancer incidence and survival rates in the Republic of Ireland, 1994-2009
Variables | Hazard ratio (95 % CI) | P-value |
|---|---|---|
Sex (reference = women) | ||
Men | 1.1 (0.9–1.3) | 0.15 |
Age (years) (reference = 30–60) | ||
< 30 | 0.3 (0.1–0.9) | 0.03 |
> 60 | 1.6 (1.4–1.9) | <0.001 |
Smoking status (reference = non-smoker) | ||
Current | 1.3 (1.1–1.5) | 0.003 |
Former smoker | 1.0 (0.8–1.3) | 0.8 |
Unknown | 1.5 (1.2–1.8) | 0.001 |
Marital status (reference = married) | ||
Divorced | 1.7 (1.1–2.7) | 0.02 |
Single | 1.2 (1.1–1.4) | 0.002 |
Other | 1.3 (1.2–1.5) | <0.001 |
Occupation status (reference = employed) | ||
Unemployed | 1.3 (1.1–1.6) | 0.003 |
Retired | 1.5 (1.3–1.9) | <0.001 |
Other | 1.1 (0.9–1.4) | 0.18 |
Deprivation index (reference = most deprived) | ||
Less deprived | 0.9 (0.8–0.9) | 0.03 |
Years of incidence (reference = 1994–1999) | ||
2000–2004 | 0.8 (0.7–0.9) | 0.01 |
2005–2009 | 0.7 (0.6–0.8) | <0.001 |
Tumour site (reference = C03 Gum) | ||
C01Base of the tongue | 1.3 (1.1–1.7) | 0.01 |
C02 Tongue | 1.3 (1.0–1.6) | 0.04 |
C04 Floor of mouth | 1.2 (0.9–1.5) | 0.11 |
C05 Unspecified mouth | 1.1 (0.5–0.8) | 0.62 |
C06 Palate | 1.1 (0.8–1.4) | 0.55 |
Cancer stages (reference = Stage I) | ||
Stage II | 1.4 (1.1–1.7) | 0.004 |
Stage III | 1.8 (1.5–2.3) | <0.001 |
Stage IV | 2.8 (2.3–3.3) | <0.001 |
Unknown stage | 1.7 (1.4–2.1) | <0.001 |