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Table 3 Interaction between ICS use and lung infections

From: Post-inhaled corticosteroid pulmonary tuberculosis and pneumonia increases lung cancer in patients with COPD

 

HR (95 % CI)

p for ICS x pulmonary infection interaction

No ICS

ICS

Model 1

 No lung infection

1

0.89 (0.68–1.16)

0.084

 TB

1.42 (0.89–2.26)

2.48 (1.31–4.72)

Model 2

 No lung infection

1

0.88 (0.67–1.15)

0.259

 Pneumonia

0.93 (0.60–1.44)

1.17 (0.69–1.99)

Model 3

 No lung infection

1

0.88 (0.67–1.16)

0.386

 TB+pneumonia

1.65 (0.76–3.58)

2.38 (1.01–5.58)

  1. Each model was adjusted by sex, age, medications, comorbidities, inpatient and outpatient visits for respiratory diseases, and urbanization