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Table 1 Clinical-pathological characteristics of studied groups of patients

From: Molecular profile of 5-fluorouracil pathway genes in colorectal carcinoma

Characteristics Testing set Validation set I Validation set II
  (n = 52) (n = 67) (n = 32)
Gender (male/female) 36/16 45/22 19/13
Age at diagnosisa 63.9 ± 9.2 years 70.2 ± 9.5 years 70.8 ± 11.2 years
Tumor size (pT)
 pT2 3 - 4
 pT3 40 62 24
 pT4 9 5 4
Presence of lymph node metastasis (pN)
 pN0 15 67 18
 pN1-2 37 - 14
Presence of distant metastasis (pM)
 pM0 26 67 32
 pM1 26 - -
Stage
 UICC II 8 67 18
 UICC III 18 - 14
 UICC IV 26 - -
Histological grade (G)b
 GI 6 9 6
 GII 39 47 19
 GIII 7 8 3
 Gx - 3 4
Primary localization
 Colon 26 44 28
 Rectosigmoideum 12 9 1
 Rectum 14 14 3
Chemotherapy
 5-FU-based 52 24c 17
 None - 33c 15
  1. Footnotes:
  2. aMedian ± standard deviation
  3. b GI well differentiated, GII moderately differentiated, GIII poorly differentiated, Gx cannot be assessed
  4. cNumbers may not add up to 67 of available subjects because of missing data (n = 10)