Fig. 7
From: Aldehyde dehydrogenase activity plays a Key role in the aggressive phenotype of neuroblastoma
Specific ALDH1A3 KO impairs NB cell clonogenic properties. a-c Impact of ALDH1A3 specific KO was analyzed on the proliferation (a), clonogenic (b), and TIC self-renewal (c) capacities. a Mean OD at 405 nm ± SD of 3 experiments performed in quadruplicates. b Mean of relative colony numbers ± SD of 3 experiments performed in duplicates (unpaired t-test *p < 0.05). c Mean ratio of cell number/cell plated ± SD of 3 experiments performed in duplicates in pooled s1 to s3 passages (s1-s3) (unpaired t-test **p ≤ 0.005)