Skip to main content

Table 3 Univariable associations of physician readiness to act on genomic risk assessment (GUCY2C) for pN0 colon cancer Patients

From: A survey of physician receptivity to molecular diagnostic testing and readiness to act on results for early-stage colon cancer patients

Variable Total (n = 41) Ready (n = 17) Not ready (n = 24) p-value
n (%) n (%) n (%)
Practice Environment:
 Practice Setting     0.748
  Community-based or Other 24 (58.54) 9 (37.50) 15 (62.50) .
  Academic Center-based 17 (41.46) 8 (47.06) 9 (52.94) .
Sociodemographic Background and Experience:
 Age     0.350
  <50 21 (51.22) 7 (33.33) 14 (66.67) .
  50+ 20 (48.78) 10 (50.00) 10 (50.00) .
 Gender     1.000
  Male 34 (82.93) 14 (41.18) 20 (58.82) .
  Female 7 (17.07) 3 (42.86) 4 (57.14) .
 Race     0.103
  (missing/unknown) 1 (.)   1 (.) .
  Asian 13 (32.50) 3 (23.08) 10 (76.92) .
  White 27 (67.50) 14 (51.85) 13 (48.15) .
 Hispanic/Latino     1.000
  No 40 (97.56) 17 (42.50) 23 (57.50) .
  Yes 1 (2.44)   1 (100.0) .
 Years in Practice     0.559
  < =10 4 (9.76) 2 (50.00) 2 (50.00) .
  10–20 11 (26.83) 3 (27.27) 8 (72.73) .
  >20 26 (63.41) 12 (46.15) 14 (53.85) .
 Specialty     1.000
  Medical Oncologists+ 23 (56.10) 10 (43.48) 13 (56.52) .
  GI Surgeons 18 (43.90) 7 (38.89) 11 (61.11) .
 Number of newly diagnosed pN0 colon cancer patients seen in past 12 months     0.679
  <5 6 (14.63) 3 (50.00) 3 (50.00) .
  5+ 35 (85.37) 14 (40.00) 21 (60.00) .
 Percentage of pN0 colon cancer patients who have had a recurrence in the past 12 months     0.530
  None 20 (48.78) 7 (35.00) 13 (65.00) .
  1+ 21 (51.22) 10 (47.62) 11 (52.38) .
 On average how many pN0 colon cancer patients do you see each month?     0.499
  <5 28 (68.29) 13 (46.43) 15 (53.57) .
  5+ 13 (31.71) 4 (30.77) 9 (69.23) .
Perceptions about Diagnostic/Prognostic Testing
 Belief in accuracy of histopathology     0.742
  Not Agree 14 (34.15) 5 (35.71) 9 (64.29) .
  Agree 27 (65.85) 12 (44.44) 15 (55.56) .
 Belief in accuracy of GUY2C testing     0.012
  Not Agree 17 (41.46) 3 (17.65) 14 (82.35) .
  Agree 24 (58.54) 14 (58.33) 10 (41.67) .
 Belief in accuracy of combined histopathology and GUCY2C testing     0.128
  Not Agree 4 (9.76)   4 (100.0) .
  Agree 37 (90.24) 17 (45.95) 20 (54.05) .
 Belief in need for a more accurate prognostic test for pN0 colon cancer patients     1.000
  Not Agree 2 (4.88) 1 (50.00) 1 (50.00) .
  Agree 39 (95.12) 16 (41.03) 23 (58.97) .
 Belief that current staging methods are not accurate for pN0 colon cancer patients     0.062
  Not Agree 17 (41.46) 4 (23.53) 13 (76.47) .
  Agree 24 (58.54) 13 (54.17) 11 (45.83) .
 Accuracy of histopathology alone     0.861
  (missing/unknown) 1 (.) 0 (.) 1 (.) .
  Very Accurate 6 (15.00) 2 (33.33) 4 (66.67) .
  Somewhat Accurate 31 (77.50) 14 (45.16) 17 (54.84) .
  Not Accurate 3 (7.50) 1 (33.33) 2 (66.67) .
  Don’t Know 0 (0.0) 0 (0.0) 0 (0.0)  
 Accuracy of GUCY2C testing alone     0.179
  (missing/unknown) 2 (.) 0 (.) 2 (.) .
  Very Accurate 6 (15.38) 5 (83.33) 1 (16.67) .
  Somewhat Accurate 22 (56.41) 9 (40.91) 13 (59.09) .
  Not Accurate 3 (7.69) 1 (33.33) 2 (66.67) .
  Don’t Know 8 (20.51) 2 (25.00) 6 (75.00) .
 Accuracy of combined histopathology and GUCY2C testing     0.084
  (missing/unknown) 1 (.) 0 (.) 1 (.) .
  Very Accurate 25 (62.50) 14 (56.00) 11 (44.00) .
  Somewhat Accurate 11 (27.50) 2 (18.18) 9 (81.82) .
  Not Accurate 0 (0.0) 0 (0.0) 0 (0.0)  
  Don’t Know 4 (10.00) 1 (25.00) 3 (75.00) .
Perceptions about Treatment
 Stress from uncertainty in decision making about treatment for pN0 colon cancer patients (scale)     0.216
  Not Agree (<=3) 22 (53.66) 7 (31.82) 15 (68.18) .
  Agree (>3) 19 (46.34) 10 (52.63) 9 (47.37) .
 Belief that treatment decision making for pN0 colon cancer patients is easy     0.499
  Not Agree 13 (31.71) 4 (30.77) 9 (69.23) .
  Agree 28 (68.29) 13 (46.43) 15 (53.57) .
 Confidence in treatment decision making for pN0 colon cancer patients     0.729
  Not Agree 12 (29.27) 4 (33.33) 8 (66.67) .
  Agree 29 (70.73) 13 (44.83) 16 (55.17) .
 Belief that treatment choice for pN0 colon cancer patients is clear     0.025
  Not Agree 19 (46.34) 4 (21.05) 15 (78.95) .
  Agree 22 (53.66) 13 (59.09) 9 (40.91) .