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Fig. 4 | BMC Cancer

Fig. 4

From: The effect of a germline mutation in the APC gene on β-catenin in human embryonic stem cells

Fig. 4

Wnt-β-catenin/TCF-mediated activity in hESC lines. a FAP1, FAP2 and normal APC hESC lines of high passage were transfected with pTOPFLASH or pFOPFLASH and Renilla (FAP1 passage 82, FAP2 passage 80, HEFX1 passage 45, HUES64 passage 48, HUES6 passage 53,), and their lysates were measured for luciferase activity. b FAP1 early (passage 12) and FAP1 high (passage 82) were measured for their luciferase activity. These data describe relative mean values (±STDV) of three independent experiments performed in duplicates. Welch's t-test between each one of the pairs was performed

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