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Fig. 4 | BMC Cancer

Fig. 4

From: ΔNp63α expression induces loss of cell adhesion in triple-negative breast cancer cells

Fig. 4

Different effects of ΔNp63α on cell adhesion/proliferation in BT-20 and BT-549 cells. BT-20 and BT-549 cells were transiently transfected with pcDNA3-ΔNp63α and pcDNA3-GFP plasmids and analyzed by xCELLigence 24 h after transfection. Cell index was significantly decreased in BT-20 cells expressing ΔNp63α (p < 0.01, t-test) and MDA-MB-468-ΔNp63α cells treated with tetracycline (p < 0.01, t-test) but not in BT-549 cells expressing ΔNp63α (p = 0.15, t-test) after 48 h. Expression of ΔNp63α 24 h after transfection / tetracycline treatment was confirmed by western blot

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