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Table 2 Treatment related toxicities

From: With or without reirradiation in advanced local recurrent nasopharyngeal carcinoma: a case–control study

 

RT+/-chemotherapy group

non-RT + chemotherapy group

 

No.of patients (%)

No.of patients (%)

P value

Grade3-5 Anemia

  

0.808

 No

33 (75.0 %)

32 (72.7 %)

 

 Yes

11 (25.0 %)

12 (27.3 %)

 

Grade3-5 Neutropenia

 

0.513

 No

28 (63.6 %)

25 (56.8 %)

 

 Yes

16 (36.4 %)

19 (43.2 %)

 

Grade3-5 Thrombocytopenia

 

0.817

 No

30 (68.2 %)

31 (70.5 %)

 

 Yes

14 (31.8 %)

13 (29.5 %)

 

Grade3-5 Mucositis

 

0.001

 No

34 (77.3 %)

44 (100.0 %)

 

 Yes

10 (22.7 %)

0 (0 %)

 

Grade3-5 Xerostomia

 

0.053

 No

35 (79.5 %)

42 (95.5 %)

 

 Yes

9 (20.5 %)

2 (4.5 %)

 

Grade3-5 Nasopharyngeal necrosis

 

<0.001

 No

27 (61.4 %)

44 (100.0 %)

 

 Yes

17 (38.6 %)

0 (0 %)

 

Grade3-5 Temporal lobe necrosis

 

0.035

 No

36 (81.8 %)

43 (97.7 %)

 

 Yes

8 (18.2 %)

1 (2.3 %)

 

Grade3-5 Cranial neuropathy

 

0.026

 No

38 (86.4 %)

44 (100.0 %)

 

 Yes

6 (13.6 %)

0 (0 %)

 

Grade3-5 Trismus

  

 No

35 (79.5 %)

44 (100.0 %)

0.002

 Yes

9 (20.5 %)

0 (0 %)

 

Grade3-5 Hearing loss

 

0.001

 No

28 (63.6 %)

42 (95.5 %)

 

 Yes

16 (36.4 %)

2 (4.5 %)

 
  1. Abbreviations: RT radiation therapy, Re-RT+/-chemotherapy radiation therapy with or without chemotherapy, non-RT + chemotherapy chemotherapy alone