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Fig. 5 | BMC Cancer

Fig. 5

From: Insulin growth factor 1 like receptor (IGF-1R)

Fig. 5

Phosphorylation of EGFR Y845 is reduced with IGF-1R specific inhibitor picropodophyllin (PPP). a Representative western blot of EGFR Y845 show decreased levels in response to 0.5 μM concentration PPP with time in both resistant cells (left panel) and in sensitive cells (right panel) The inhibitory effect of PPP is more rapid in resistant as compared to sensitive cells. b similar treatment times as in (a), but monitored effect using 10 μM AG1024, another inhibitor of IGF-1R. Note that AG1024 is less inhibitory to IGF1R than PPP

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BMC Cancer

ISSN: 1471-2407

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