Table 4 Odds ratios per 5 kg/m² increase of BMI at age 20, BMI at age 50, current BMI and BMI changes stratified by BMI at age 20, current age and current MHT use

p interaction

OR^a

95 % CI

p trend^b

OR^a

95 % CI

p trend^b

BMI at age 50

1.36

[0.88-2.01]

0.16

1.08

[0.93-1.25]

0.31

0.52

Current BMI

1.47

[1.05-2.07]

0.02

0.99

[0.88-1.12]

0.91

0.14

BMI gain, age 20-40

1.05

[0.60-1.85]

0.85

0.85

[0.70-1.03]

0.09

0.46

BMI gain, age 40-50

2.06

[1.09-3.88]

0.02

1.29

[1.00-1.65]

0.05

0.40

BMI gain, age 50 to current age

1.62

[0.96-2.74]

0.06

0.94

[0.76-1.15]

0.53

0.28

p interaction

OR^a

95 % CI

p trend^b

OR^a

95 % CI

p trend^b

BMI at age 20

1.04

[0.82-1.33]

0.74

1.07

[0.77-1.47]

0.69

0.76

BMI at age 50

1.03

[0.88-1.21]

0.68

1.27

[0.98-1.63]

0.06

0.07

Current BMI

0.97

[0.84-1.11]

0.66

1.18

[0.98-1.42]

0.08

0.08

BMI gain, age 20-40

0.83

[0.67-1.04]

0.10

1.06

[0.74-1.50]

0.75

0.20

BMI gain, age 40-50

1.24

[0.95-1.61]

0.11

1.88

[1.14-3.07]

0.01

0.08

BMI gain, age 50 to current age

0.97

[0.74-1.27]

0.82

1.04

[0.80-1.36]

0.76

0.87

p interaction

OR^a

95 % CI

p trend ^b

OR^a

95 % CI

p trend^b

BMI at age 20

0.97

[0.54-1.74]

0.91

1.03

[0.84-1.26]

0.81

0.81

BMI at age 50

1.05

[0.69-1.60]

0.81

1.07

[0.93-1.24]

0.31

0.75

Current BMI

1.08

[0.77-1.50]

0.65

1.03

[0.92-1.16]

0.63

0.90

BMI gain, age 20-40

1.27

[0.72-2.24]

0.40

0.86

[0.70-1.04]

0.13

0.73

BMI gain, age 40-50

1.02

[0.47-2.20]

0.97

1.37

[1.08-1.74]

0.01

0.34

BMI gain, age 50 to current age

1.06

[0.59-1.88]

0.85

1.00

[0.82-1.22]

0.99

0.69