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Table 2 Baseline characteristics of studies included in the meta-analysis

From: Internal jugular vein versus subclavian vein as the percutaneous insertion site for totally implantable venous access devices: a meta-analysis of comparative studies

Study Country Design Participants Use of heparin flushing Antibiotic prophylaxis Ultrasound guidance Matching criteriaa Follow-upb, IJV/SCV
Age, yr (median/mean) Range TIVAD IJV SCV
Araujoc [15], 2008 Portugal PC 55.5 (median) 15–83 Mini-sitimplant 512 551 Y N N 1,2,3,4,5 244/363d (median)
Biffi [16], 2009 Italy RCT 51.9 (mean) 18–75 Bard Port 117 123 Y NR Only for SCV 1,2,4,6,7,8 384/360d (median)
Plumhans [31], 2011 Germany PC 56 (mean) 18–85 Bard Port 44 94 Y NR Only for IJV 7,8 6 mo (mean)
Aribaş [38], 2012 Turkey RC 53.8 (mean) 16–84 Polysite 248 99 Y NR Y 1,2,4,7,8 219.5d (mean)
Ribeiro [39], 2012 Brazil RCT < 18 yr NR NR 34 43 Y Y N 1,2,4,6,7,8 14.8/12.6 mo (mean)
Vetter [21], 2013 Germany RC 53 (mean) 2–84 INTRAPORT 71 32 Y Y N 1,2 451d (mean)
Liud [40], 2014 China RC 45.4 (mean) 8–86 Bardport 222 398 Y NR N 1,2,3,4 1079.3/995.2d (mean)
Miao [41], 2014 China RCT 58.1 (mean) 25–81 NR 107 107 Y Y Only for IJV 1,2,3,4,8 215/209d (mean)
Nagasawae [17], 2014 Japan RC 64 (median) 25–85 BARD X-port isp 136 97 NR NR Only for IJV 3 566/402d (mean)
Ozbudak [42], 2014 Turkey RC 56.38 (mean) 14–83 FB Medical/Districlass medical SA 178 224 Y N Y for some patients 3,8 507d (median)
Wu [18], 2014 Taiwan RC 57.7 (mean) 0.5–94 Arrow/Bard/ Tyco 63 234 Y NR N NA 4.5 yr (mean)
Jung [23], 2015 Korea RC 59 (median) 1–82 Bard Port 92 79 NR NR N 1,2,4,7 278d (median)
  1. Abbreviations: d days, mo months, N No, NR data not reported, PC prospective cohort study, RC retrospective cohort study, US ultrasound guidance, Y Yes, yr years
  2. afor matching criteria: 1 = age; 2 = gender; 3 = completion of the TIVAD insertion; 4 = site of primary malignancy; 5 = time of surgery; 6 = side; 7 = TIVAD outer diameter; 8 = coagulation parameters; 9 = body mass index
  3. bMean or median dwell time
  4. cOnly 512 and 551 patients were included in the analysis for group IJV and SCV respectively
  5. dOne catheter fracture due to iatrogenic injury was not included in the analysis
  6. eOne case of pin hole leakage in the IJV arm was included in the major mechanical complications