|
Study
|
Country
|
Design
|
Participants
|
Use of heparin flushing
|
Antibiotic prophylaxis
|
Ultrasound guidance
|
Matching criteriaa
|
Follow-upb, IJV/SCV
|
|---|
|
Age, yr (median/mean)
|
Range
|
TIVAD
|
IJV
|
SCV
|
|---|
|
Araujoc [15], 2008
|
Portugal
|
PC
|
55.5 (median)
|
15–83
|
Mini-sitimplant
|
512
|
551
|
Y
|
N
|
N
|
1,2,3,4,5
|
244/363d (median)
|
|
Biffi [16], 2009
|
Italy
|
RCT
|
51.9 (mean)
|
18–75
|
Bard Port
|
117
|
123
|
Y
|
NR
|
Only for SCV
|
1,2,4,6,7,8
|
384/360d (median)
|
|
Plumhans [31], 2011
|
Germany
|
PC
|
56 (mean)
|
18–85
|
Bard Port
|
44
|
94
|
Y
|
NR
|
Only for IJV
|
7,8
|
6 mo (mean)
|
|
Aribaş [38], 2012
|
Turkey
|
RC
|
53.8 (mean)
|
16–84
|
Polysite
|
248
|
99
|
Y
|
NR
|
Y
|
1,2,4,7,8
|
219.5d (mean)
|
|
Ribeiro [39], 2012
|
Brazil
|
RCT
|
< 18 yr
|
NR
|
NR
|
34
|
43
|
Y
|
Y
|
N
|
1,2,4,6,7,8
|
14.8/12.6 mo (mean)
|
|
Vetter [21], 2013
|
Germany
|
RC
|
53 (mean)
|
2–84
|
INTRAPORT
|
71
|
32
|
Y
|
Y
|
N
|
1,2
|
451d (mean)
|
|
Liud [40], 2014
|
China
|
RC
|
45.4 (mean)
|
8–86
|
Bardport
|
222
|
398
|
Y
|
NR
|
N
|
1,2,3,4
|
1079.3/995.2d (mean)
|
|
Miao [41], 2014
|
China
|
RCT
|
58.1 (mean)
|
25–81
|
NR
|
107
|
107
|
Y
|
Y
|
Only for IJV
|
1,2,3,4,8
|
215/209d (mean)
|
|
Nagasawae [17], 2014
|
Japan
|
RC
|
64 (median)
|
25–85
|
BARD X-port isp
|
136
|
97
|
NR
|
NR
|
Only for IJV
|
3
|
566/402d (mean)
|
|
Ozbudak [42], 2014
|
Turkey
|
RC
|
56.38 (mean)
|
14–83
|
FB Medical/Districlass medical SA
|
178
|
224
|
Y
|
N
|
Y for some patients
|
3,8
|
507d (median)
|
|
Wu [18], 2014
|
Taiwan
|
RC
|
57.7 (mean)
|
0.5–94
|
Arrow/Bard/ Tyco
|
63
|
234
|
Y
|
NR
|
N
|
NA
|
4.5 yr (mean)
|
|
Jung [23], 2015
|
Korea
|
RC
|
59 (median)
|
1–82
|
Bard Port
|
92
|
79
|
NR
|
NR
|
N
|
1,2,4,7
|
278d (median)
|
- Abbreviations: d days, mo months, N No, NR data not reported, PC prospective cohort study, RC retrospective cohort study, US ultrasound guidance, Y Yes, yr years
- afor matching criteria: 1 = age; 2 = gender; 3 = completion of the TIVAD insertion; 4 = site of primary malignancy; 5 = time of surgery; 6 = side; 7 = TIVAD outer diameter; 8 = coagulation parameters; 9 = body mass index
- bMean or median dwell time
- cOnly 512 and 551 patients were included in the analysis for group IJV and SCV respectively
- dOne catheter fracture due to iatrogenic injury was not included in the analysis
- eOne case of pin hole leakage in the IJV arm was included in the major mechanical complications
