Fig. 1
From: The circadian clock modulates anti-cancer properties of curcumin
Circadian rhythms in mPer2 clock gene expression persist after treatment with 5 μM curcumin. (a) Signal from the mPer2::mPer2:luc reporter gene after a forskolin pulse used to synchronize cellular circadian oscillators is shown as the hourly integrated light signal (relative light units averaged from 4 independent cultures). (b) A significant period of 24.48 h was detected by Lomb-Scargle Periodogram analysis (p < 0.001) is shown in the frequency spectrum