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Table 3 Univariate analyses of risk factors of pneumothorax in STS patients during pazopanib treatment

From: Risk factors for pneumothorax in advanced and/or metastatic soft tissue sarcoma patients during pazopanib treatment: a single-institute analysis

Pneumothorax Present (n = 6) Absent (n = 52)  
Variants No. % No. % p-value
Gender
 Male 5 83 29 56 0.097
 Female 1 17 23 44
Pathological diagnosis
 Synovial sarcoma 3 50 6 12 0.042
 Others 3 50 46 88
Hypertension
 Present 1 17 9 17 1.00
 Absent 5 83 43 83
Smoking history
 Present 3 50 17 33 0.41
 Absent 3 50 35 67
Smoking index ≥ 400
 Present 2 33 4 8 0.11
 Absent 4 67 48 92
Lung lesion
 Present 6 100 35 67 0.17
 Absent 0 0 17 33
Pleural lesion
 Present 4 67 19 37 0.20
 Absent 2 33 33 63
No. of lung lesions
 0–1 0 0 29 56 0.072
 2 or more 6 100 23 44
Maximum dia. of lung lesions
  ≥ 30 mm 5 83 16 31 0.02
  < 30 mm 1 17 36 69
History of lung surgery
 Present 2 33 19 37 1.00
 Absent 4 67 33 63
History of pneumothorax
 Present 2 33 2 4 0.049
 Absent 4 67 50 96