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Table 3 Univariate analyses of risk factors of pneumothorax in STS patients during pazopanib treatment

From: Risk factors for pneumothorax in advanced and/or metastatic soft tissue sarcoma patients during pazopanib treatment: a single-institute analysis

Pneumothorax

Present (n = 6)

Absent (n = 52)

 

Variants

No.

%

No.

%

p-value

Gender

 Male

5

83

29

56

0.097

 Female

1

17

23

44

Pathological diagnosis

 Synovial sarcoma

3

50

6

12

0.042

 Others

3

50

46

88

Hypertension

 Present

1

17

9

17

1.00

 Absent

5

83

43

83

Smoking history

 Present

3

50

17

33

0.41

 Absent

3

50

35

67

Smoking index ≥ 400

 Present

2

33

4

8

0.11

 Absent

4

67

48

92

Lung lesion

 Present

6

100

35

67

0.17

 Absent

0

0

17

33

Pleural lesion

 Present

4

67

19

37

0.20

 Absent

2

33

33

63

No. of lung lesions

 0–1

0

0

29

56

0.072

 2 or more

6

100

23

44

Maximum dia. of lung lesions

  ≥ 30 mm

5

83

16

31

0.02

  < 30 mm

1

17

36

69

History of lung surgery

 Present

2

33

19

37

1.00

 Absent

4

67

33

63

History of pneumothorax

 Present

2

33

2

4

0.049

 Absent

4

67

50

96