Table 3 Interaction between SNPs in miRNAs and cooking oil exposure on lung adenocarcinoma in Chinese non-smoking female population
SNP | Oil | No of controls (%) | No of cases (%) | OR (95 % CI) | P value |
|---|---|---|---|---|---|
rs10459194 | |||||
TT | Non-exposure | 166 (62.4) | 100 (50.8) | 1.00 (ref) | — |
TC + CC | Non-exposure | 34 (12.8) | 26 (13.2) | 1.269 (0.720–2.240) | 0.410 |
TT | Exposure | 53 (19.9) | 51 (25.9) | 1.597 (1.011–2.524) | 0.045 |
TC + CC | Exposure | 13 (4.9) | 20 (10.2) | 2.554 (1.217–5.358) | 0.013 |
rs10988341 | |||||
AA | Non-exposure | 147 (55.3) | 87 (44.2) | 1.00 (ref) | — |
AG + GG | Non-exposure | 53 (19.9) | 39 (19.8) | 1.243 (0.761–2.032) | 0.385 |
AA | Exposure | 48 (18.0) | 49 (24.9) | 1.725 (1.069–2.783) | 0.025 |
AG + GG | Exposure | 18 (6.8) | 22 (11.2) | 2.065 (1.049–4.064) | 0.036 |
rs1514035 | |||||
AG + GG | Non-exposure | 36 (13.5) | 20 (10.2) | 1.00 (ref) | — |
AA | Non-exposure | 164 (61.7) | 106 (53.8) | 1.163 (0.639–2.117) | 0.620 |
AG + GG | Exposure | 17 (6.4) | 12 (6.1) | 1.271 (0.507–3.186) | 0.610 |
AA | Exposure | 49 (18.4) | 59 (29.9) | 2.167 (1.115–4.215) | 0.023 |