Table 2 Interaction between SNPs in miRNAs and cooking oil exposure on lung cancer susceptibility in Chinese non-smoking female population
SNP | Oil | No of controls (%) | No of cases (%) | OR (95 % CI) | P value |
|---|---|---|---|---|---|
rs10459194 | |||||
TT | Non-exposure | 166 (62.4) | 133 (49.6) | 1.00 (ref) | — |
TC + CC | Non-exposure | 34 (12.8) | 35 (13.1) | 1.285 (0.761–2.170) | 0.349 |
TT | Exposure | 53 (19.9) | 77 (28.7) | 1.813 (1.194–2.753) | 0.005 |
TC + CC | Exposure | 13 (4.9) | 23 (8.6) | 2.208 (1.078–4.524) | 0.030 |
rs10988341 | |||||
AA | Non-exposure | 147 (55.3) | 117 (43.7) | 1.00 (ref) | — |
AG + GG | Non-exposure | 53 (19.9) | 51 (19.0) | 1.209 (0.767–1.905) | 0.413 |
AA | Exposure | 48 (18.0) | 69 (25.7) | 1.806 (1.162–2.808) | 0.009 |
AG + GG | Exposure | 18 (6.8) | 31 (11.6) | 2.164 (1.153–4.061) | 0.016 |
rs1514035 | |||||
AG + GG | Non-exposure | 36 (13.5) | 27 (10.1) | 1.00 (ref) | — |
AA | Non-exposure | 164 (61.7) | 141 (52.6) | 1.146 (0.663–1.982) | 0.625 |
AG + GG | Exposure | 17 (6.4) | 22 (8.2) | 1.725 (0.771–3.963) | 0.185 |
AA | Exposure | 49 (18.4) | 78 (29.1) | 2.122 (1.149–3.921) | 0.016 |