Fig. 4
Hypoxia inhibits MTX-induced cell death pathways in Reh cells. a Effect of several concentrations of MTX over 24 h on Reh cells maintained in normoxia (21 % O2) or in hypoxia (5 % O2) on 10 pro-apoptotic proteins. b Effect of several concentrations of MTX over 24 h on Reh cells maintained in normoxia (21 % O2) or in hypoxia (5 % O2) on 3 anti-apoptotic proteins. Proteomic analysis was performed by RPPA. Data are represented by experimental conditions and by protein expressions after Z-score normalization. Protein expressions with two standard deviations away from the mean were analyzed