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Fig. 2 | BMC Cancer

Fig. 2

From: Hypoxia promotes chemoresistance in acute lymphoblastic leukemia cell lines by modulating death signaling pathways

Fig. 2

Hypoxia dampens MTX and PRD effect on leukemic cells viability without affecting viable cell density. a Effect of hypoxia (5 % O2) on viable cell density of leukemic cells treated with several concentrations of MTX or PRD at 72 h. b Effect of hypoxia (5 % O2) on viability of leukemic cells treated with several concentrations of MTX or PRD at 72 h. Viable cell density and percentage of cell viability measurement were performed by an automatic cell counter. All results are representatives with mean ± S.E.M. of 4 independent experiments. *indicates p < 0.05; **p < 0.01; ***p < 0.001 vs normoxia (21 % O2)

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