Table 1 Differentially expressed significant genes in RCC
Gene symbol | Gene name | RefSeq | p-value | Fold-change |
|---|---|---|---|---|
HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | NM_001040708 | 7.88E-06 | 3.64128 |
NRP2 | neuropilin 2 | ENST00000272849 | 0.00017 | 3.63215 |
LEF1 | lymphoid enhancer-binding factor 1 | NM_001130713 | 4.04E-05 | 3.54448 |
HIST1H3H | histone cluster 1, H3h | NM_003536 | 3.29E-05 | 2.87948 |
ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) | NM_000887 | 3.23E-05 | 2.69367 |
BUB1 | BUB1 mitotic checkpoint serine | NM_001278616 | 3.35E-05 | 2.62163 |
MAP3K7CL | MAP3K7 C-terminal like | NM_001286620 | 2.81E-05 | 2.54523 |
FXYD5 | FXYD domain containing ion transport regulator 5 | NM_001164605 | 0.000158 | 2.45618 |
HIST1H2AI | histone cluster 1, H2ai | NM_003509 | 0.000108 | 2.27918 |
CENPK | centromere protein K | NM_001267038 | 6.01E-05 | 2.27502 |
CCND1 | cyclin D1 | NM_053056 | 0.004789 | 2.25898 |
DDX11 | DEAD | NM_001257144 | 0.000178 | 2.24119 |
APOBEC3D | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-li | NM_152426 | 2.61E-06 | 2.23905 |
ATAD2 | ATPase family, AAA domain containing 2 | NM_014109 | 0.000129 | 2.18905 |
HIST1H3F | histone cluster 1, H3f | NM_021018 | 0.00016 | 2.14196 |
TREM2 | triggering receptor expressed on myeloid cells 2 | NM_018965 | 0.00021 | 2.13092 |
GAL3ST4 | galactose-3-O-sulfotransferase 4 | NM_024637 | 1.50E-05 | 2.11736 |
LOC400464 | uncharacterized LOC400464 | AK127420 | 9.33E-05 | 2.11281 |
CXCL11 | chemokine (C-X-C motif) ligand 11 | NM_005409 | 0.0002 | 2.07422 |
NEIL3 | nei endonuclease VIII-like 3 (E. coli) | NM_018248 | 2.73E-05 | 2.06874 |
EVL | Enah | ENST00000553771 | 5.57E-05 | 2.06506 |
SLFN12L | schlafen family member 12-like | ENST00000361112 | 9.07E-05 | 2.02832 |
ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 | NM_001161504 | 4.94E-07 | −16.1809 |
SLC22A12 | solute carrier family 22 (organic anion | NM_001276326 | 9.50E-06 | −16.4997 |
SLC47A2 | solute carrier family 47 (multidrug and toxin extrusion), me | NM_001099646 | 5.60E-06 | −17.2214 |
HAO2 | hydroxyacid oxidase 2 (long chain) | NM_001005783 | 0.000192 | −17.3322 |
SLC6A19 | solute carrier family 6 (neutral amino acid transporter), me | NM_001003841 | 0.000195 | −18.4585 |
XPNPEP2 | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound | NM_003399 | 0.000131 | −18.9386 |
CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | XR_246241 | 7.59E-05 | −19.2237 |
SLC22A6 | solute carrier family 22 (organic anion transporter), member 6 | NM_004790 | 5.33E-06 | −20.6522 |
KCNJ1 | potassium inwardly-rectifying channel, subfamily J, member 1 | NM_000220 | 8.79E-05 | −22.4359 |
TMEM52B | transmembrane protein 52B | NM_001079815 | 0.000112 | −23.1374 |
SLC12A3 | solute carrier family 12 (sodium | NM_000339 | 1.14E-06 | −27.7638 |
HPD | 4-hydroxyphenylpyruvate dioxygenase | NM_001171993 | 1.88E-05 | −29.7949 |
SLC5A12 | solute carrier family 5 (sodium | XM_006718157 | 0.000155 | −30.9613 |
KNG1 | kininogen 1 | NM_000893 | 4.28E-06 | −34.7144 |
SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate tra | NM_001011554 | 1.93E-06 | −37.6483 |
SLC36A2 | solute carrier family 36 (proton | NM_181776 | 4.06E-07 | −37.8957 |
PLG | plasminogen | NM_000301 | 4.87E-07 | −43.0535 |
SLC22A8 | solute carrier family 22 (organic anion transporter), member | NM_001184732 | 4.50E-06 | −45.8474 |
UMOD | uromodulin | NM_001008389 | 2.44E-06 | −68.9599 |
CALB1 | calbindin 1, 28 kDa | NM_004929 | 2.29E-06 | −78.3947 |
SLC12A1 | solute carrier family 12 | ENST00000330289 | 0.000135 | −79.6698 |
ALDOB | aldolase B, fructose-bisphosphate | NM_000035 | 2.56E-05 | −87.9122 |