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Fig. 7 | BMC Cancer

Fig. 7

From: Primary breast cancer cell culture yields intra-tumor heterogeneous subpopulations expressing exclusive patterns of receptor tyrosine kinases

Fig. 7

Effect of the combinations Crizotinib-Imatinib, and Lapatinib-Imatinib on cell viability. MBCDF and its subpopulations: D5, B6, B3, C1 (Group 1, left panel), F3, C9, B2 (Group 2, right panel) were seeded as in Fig. 5. a Crizotinib was used at the following concentrations: 0, 0.1, 0.5 and 1 μM with Imatinib 1 μM. b Lapatinib was added at 0, 0.05, 0.1, 0.5 μM plus Imatinib 1 μM. Cell viability was evaluated as in Fig. 5. Data represent the mean ± SEM of three independent experiments seeded in triplicate. * P < 0.05 versus Crizotinib or Lapatinib alone

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BMC Cancer

ISSN: 1471-2407

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