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Fig. 1 | BMC Cancer

Fig. 1

From: Bicyclol induces cell cycle arrest and autophagy in HepG2 human hepatocellular carcinoma cells through the PI3K/AKT and Ras/Raf/MEK/ERK pathways

Fig. 1

The effect of bicyclol on the living cell number of cancer cell lines and normal liver cells. a Chemical structure of bicyclol. b The effect of various concentrations of bicyclol on HepG2, Hela and LO2 cells after 48 h of treatment. DMSO-treated (0.25 %) cells were used as vehicle controls. A570 was measured after the MTT incubation. c dose- and time-dependent effect of bicyclol on the living cell number of HepG2 cells. The bar graphs represent the means ± SD from three independent experiments. d The IC50 values at 48 h in different cells. The bar graphs represent the 95 % confidence intervals

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