|Inclusion criteria||Exclusion criteria|
• Patients receiving anthracycline or trastuzumab-based chemotherapy.|
• Histologically confirmed malignancy;
• Age > 18 years, and
• No contraindication to MRI.
• Physical disability preventing exercise testing or DEXA scan;|
• Psychiatric disease or disorder precluding informed consent;
• Contraindication to anti-cancer therapy, including known heart failure, cardiomyopathy, or baseline LV ejection fraction less than 50 %;
• Previous anthracycline or trastuzumab-based therapy;
• Previous radiotherapy to thorax.