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Table 3 Predictive factors for pT4 according to univariate and multivariate analyses

From: Clinically suspected T4 colorectal cancer may be resected using a laparoscopic approach

  Univariate analysis Multivariate analysis
  HR 95 % CI P-value HR 95 % CI P-value
Age (years)
 >60 / ≤ 60 0.84 0.52-1.35 0.466    
Sex
 Male / Female 1.38 0.85-2.23 0.189    
BMI (kg/m2)
 >23 / ≤ 23 0.82 0.51-1.32 0.423    
PreOP CEA (ng/ml)
 >5 / ≤ 5 1.85 1.09-3.15 0.022 1.71 0.99-2.94 0.053
Tumor location
 Rectum / Colon 0.77 0.46-1.29 0.316    
Clinical T4 status
 T4b / T4a 1.56 0.96-2.54 0.076 1.43 0.75-2.43 0.179
Clinical N status
 + / - 2.09 0.56-7.75 0.272    
Clinical obstruction
 + / - 1.62 0.99-2.63 0.054 1.43 0.85-2.41 0.181
Clinical perforation
 + / - 3.22 1.37-7.56 0.007 2.77 1.15-6.67 0.024
Operative technique
 Laparoscopic / Open 0.47 0.26-0.85 0.013 0.55 0.30-1.02 0.060
  1. PreOP CEA Preoperative carcinoembryonic antigen