Table 3 Predictive factors for pT4 according to univariate and multivariate analyses
From: Clinically suspected T4 colorectal cancer may be resected using a laparoscopic approach
Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
HR | 95 % CI | P-value | HR | 95 % CI | P-value | |
Age (years) | ||||||
>60 / ≤ 60 | 0.84 | 0.52-1.35 | 0.466 | |||
Sex | ||||||
Male / Female | 1.38 | 0.85-2.23 | 0.189 | |||
BMI (kg/m2) | ||||||
>23 / ≤ 23 | 0.82 | 0.51-1.32 | 0.423 | |||
PreOP CEA (ng/ml) | ||||||
>5 / ≤ 5 | 1.85 | 1.09-3.15 | 0.022 | 1.71 | 0.99-2.94 | 0.053 |
Tumor location | ||||||
Rectum / Colon | 0.77 | 0.46-1.29 | 0.316 | |||
Clinical T4 status | ||||||
T4b / T4a | 1.56 | 0.96-2.54 | 0.076 | 1.43 | 0.75-2.43 | 0.179 |
Clinical N status | ||||||
+ / - | 2.09 | 0.56-7.75 | 0.272 | |||
Clinical obstruction | ||||||
+ / - | 1.62 | 0.99-2.63 | 0.054 | 1.43 | 0.85-2.41 | 0.181 |
Clinical perforation | ||||||
+ / - | 3.22 | 1.37-7.56 | 0.007 | 2.77 | 1.15-6.67 | 0.024 |
Operative technique | ||||||
Laparoscopic / Open | 0.47 | 0.26-0.85 | 0.013 | 0.55 | 0.30-1.02 | 0.060 |