Fig. 2
From: In vivo bioluminescence imaging for leptomeningeal dissemination of medulloblastoma in mouse models
Intracisternal injection for medulloblastoma (MB) seeding model and survival analysis. a Immune-deficient BALB/c-nude mice were mounted on the stereotactic device. The mouse heads were fixed in a stereotactic device, and the cisterna magna was exposed. MB-effLuc cells (UW426-effLuc: 1.2 × 106; MED8A-effLuc: 1.2 × 105, 3.0 × 105, 6.0 × 105 and 1.2 × 106; D283-effLuc: 1.2 × 106) were slowly injected into the subarachnoid space of the cisterna magna. b The median survival days of each group were estimated: UW426-effLuc: 22 days for 1.2 × 106 cells; D283-effLuc: 41 days for 1.2 × 106 cells; MED8A-effLuc: 57 days for 1.2 × 105 cells, 21 days for 3.0 × 105 cells, 14 days for 6.0 × 105 cells and 12 days for 1.2 × 106 cells