Fig. 3
From: Anti-cancer effects of baicalein in non-small cell lung cancer in-vitro and in-vivo
Quantification of morphologic features of apoptosis following baicalein treatment. The In Cell Analyser was used to quantify apoptosis markers following treatment with increasing concentrations of baicalein (100 nM, 1 μM, 10 μM and 100 μM) and High Content Screening. Levels of f-actin were significantly reduced by baicalein (a), while nuclear condensation (b) and mitochondrial mass/potential (c) were both increased. Cell count was also significantly reduced following treatment (d), confirming earlier observations. Data is expressed as mean ± SEM of three independent experiments (**p < 0.01, ***p < 0.0001)