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Table 2 Summary of the IC50 values (μM) and resistance factors (RF) for CS, CB and OX as applied to the ovarian cancer A2780, A2780cisR, A2780ZD0473R and SKOV-3 cell lines. IC50 is the drug concentration required for 50 % cell kill and RF is the ratio of the IC50 value in the resistant A2780cisR and A2780ZD0473R cell lines over that in the responsive parent A2780 cell line

From: Changes in the in vitro activity of platinum drugs when administered in two aliquots

  A2780 A2780cisR RF A2780ZD0473R RF SKOV-3
CS 0.5 ± 0.03 8.2 ± 0.6 17.7 6.0 ± 0.5 13.0 10.2 ± 0.5
CB 14.0 ± 1.4 48.9 ± 3.9 3.5 64.6 ± 3.2 4.6 43.4 ± 3.9
OX 0.2 ± 0.01 0.4 ± 0.02 1.9 0.4 ± 0.03 2.1 43.6 ± 3.0