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Table 1 Human ovarian cancer cell lines used in this study

From: Changes in the in vitro activity of platinum drugs when administered in two aliquots

Cell line

Phenotype

A2780

Untreated ovarian tumour

A2780cisR

CS resistant ovarian tumour

A2780ZD0473R

ZD0473a resistant ovarian tumour

SKOV-3

Oestrogen receptor positive ovarian tumour

  1. aZD0473 (also known as JM473 and AMD 473) is a sterically hindered platinum complex with a cis-geometry like cisplatin