EGFR
|
+
|
+
|
+
|
Similar levels in benign, CRC II and IV.
|
pAKT/AKT
|
+
|
+
|
+
|
Total levels of pAKT and AKT upregulated in CRC but pAKT/AKT ratios were similar in the different samples.
|
p70S6K
|
+
|
+
|
+
|
Similar levels in benign, CRC II and IV.
|
PLCγ1
|
-
|
+++
|
+ +
|
Low or no PLCγ1 expression in benign samples and higher levels in CRC. pPLCγ1 was not detected in any samples.
|
SRC pY527/SRC
|
+++
|
+
|
+
|
Low or no SRC pY418 in all samples. Lower SRC pY527/SRC ratios in CRC II and IV compared to benign.
|
pERK1/ERK1
|
+++
|
+
|
+
|
Reduced pERK1/ERK1 ratio in CRC II and IV compared to benign.
|
pERK2/ERK2
|
++
|
++
|
++
|
Similar ratios benign, CRC II and IV.
|
MEK1/2
|
+
|
+
|
+
|
Similar levels in benign, CRC II and IV.
|