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Table 3 Univariate and Multivariate survival analyses (Cox regression model) of various factors in 153 patients with breast cancer

From: Clinicopathological implications of Tiam1 overexpression in invasive ductal carcinoma of the breast

Factors DFS Hazard ratio (95 % CI) P value OS Hazard ratio (95 % CI) P value
Univariate analyses
 Age 1.172(0.851–1.616) 0.331 1.162(0.844–1.601) 0.358
 Menopausal status 1.015(0.831–1.239) 0.885 1.016(0.831–1.242) 0.878
 Molecular type 1.373(0.995–1.896) 0.054 1.385(1.004–1.912) 0.047*
 Tumor stage 0.685(0.590–0.796) 0.000** 0.694(0.599–0.805) 0.000**
 LN metastasis 1.287(0.927–1.786) 0.131 1.335(0.961–1.855) 0.085
 ER 1.171(0.848–1.616) 0.338 1.163(0.843–1.605) 0.359
 PR 1.016(0.736–1.404) 0.922 1.048(0.760–1.446) 0.774
 Her2 1.646(1.186–2.285) 0.003** 1.740(1.245–2.431) 0.001**
 Ki-67 1.058(0.765–1.4622) 0.734 1.075(0.777–1.485) 0.663
 Tiam1 1.781(1.276–2.487) 0.001** 1.671(1.204–2.320) 0.002**
Multivariate analyses
 Tiam1 1.470(1.056–2.047) 0.022* 1.549(1.112–2.157) 0.010*
 Molecular type 1.340(0.963–1.865) 0.082
 Tumor stage 0.567(0.413–0.778) 0.000** 0.585(0.425–0.805) 0.001**
 Her2 0.585(0.290–1.179) 0.134 0.617(0.298–1.276) 0.617
  1. 95 % CI 95 % confidence interval
  2. * p < 0.05, ** p < 0.01