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Table 3 Univariate and Multivariate survival analyses (Cox regression model) of various factors in 153 patients with breast cancer

From: Clinicopathological implications of Tiam1 overexpression in invasive ductal carcinoma of the breast

Factors

DFS Hazard ratio (95 % CI)

P value

OS Hazard ratio (95 % CI)

P value

Univariate analyses

 Age

1.172(0.851–1.616)

0.331

1.162(0.844–1.601)

0.358

 Menopausal status

1.015(0.831–1.239)

0.885

1.016(0.831–1.242)

0.878

 Molecular type

1.373(0.995–1.896)

0.054

1.385(1.004–1.912)

0.047*

 Tumor stage

0.685(0.590–0.796)

0.000**

0.694(0.599–0.805)

0.000**

 LN metastasis

1.287(0.927–1.786)

0.131

1.335(0.961–1.855)

0.085

 ER

1.171(0.848–1.616)

0.338

1.163(0.843–1.605)

0.359

 PR

1.016(0.736–1.404)

0.922

1.048(0.760–1.446)

0.774

 Her2

1.646(1.186–2.285)

0.003**

1.740(1.245–2.431)

0.001**

 Ki-67

1.058(0.765–1.4622)

0.734

1.075(0.777–1.485)

0.663

 Tiam1

1.781(1.276–2.487)

0.001**

1.671(1.204–2.320)

0.002**

Multivariate analyses

 Tiam1

1.470(1.056–2.047)

0.022*

1.549(1.112–2.157)

0.010*

 Molecular type

1.340(0.963–1.865)

0.082

 Tumor stage

0.567(0.413–0.778)

0.000**

0.585(0.425–0.805)

0.001**

 Her2

0.585(0.290–1.179)

0.134

0.617(0.298–1.276)

0.617

  1. 95 % CI 95 % confidence interval
  2. * p < 0.05, ** p < 0.01