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Table 1 Previously reported antemortem diagnoses of PTTM

From: Antemortem diagnosis of pulmonary tumor thrombotic microangiopathy in a patient with recurrent breast cancer: a case report

Year

Author

Primary site

Diagnostic method of PTTM

CT findings

PH

Treatment

Survival time

2007

Miyano et al. [5]

Stomach

VATS

Multiple tiny nodules

-

S-1 + dexamethasone

+ warfarin, aspirin

9 months

2008

Noguchi et al. [12]

Stomach

TBLB

Tiny nodules

+

No treatment

10 days

2008

Uruga et al. [8]

Lung

CT guided biopsy

Consolidation, ground glass attenuation

-

Carboplatin, paclitaxel

7 months

2011

Ishiguro et al. [2]

Unknown

TBLB

Mild interlobular septal thickening, ground glass opacities

+

CHOP(cyclophosphamide, doxorubicin, vincristine, prednisolone)

4 months

2011

Ueda et al. [7]

Esophagus

TBLB

Multiple bilateral diffuse interstitial infiltrative shadows

+

Fluorouracil, nedaplatin

9 days

2012

Kayatani et al. [3]

Unknown

VATS

Centrilobular ultrafine granular shadows

-

S-1, cisplatin

15 months

2013

Ogawa et al. [6]

Gastroduodenum

TBLB

A nodular shadow and septal thicken with a slight amount of pleural effusion

+

Bosentan, epoprostenol

+ imatinib

+ S-1, 5-fluorouracil

9 months

2013

Kitamura et al. [4]

Breast

TBLB

Ground glass opacities around the bronchovascular bundles

-

Irinotecan + warfarin

3 months

2014

Higo et al. [13]

Breast

Pulmonary wedge aspiration

Mosaic pattern

+

Bosentan, tadalafil

+ imatinib, bevacizumab + S-1

12 months

2015

Takahashi et al. (present case)

Breast

VATS

Peripheral consolidation in both lower lobes

-

Trastuzumab

32 months

  1. PTTM Pulmonary tumor thrombotic microangiopathy, PH pulmonary hypertension, TBLB transbronchial lung biopsy, VATS Video-assisted thoracoscopic surgery, S-1 tegafur, gimeracil oteracil potassium