Fig. 1

WES metrics comparison. Mean percentage ± SD (n = 5) of mapped, properly paired and duplicated reads obtained for each exome capture technology in both FF and FFPE libraries (a). Mean percentage ± SD (n = 5) of target bases achieving a certain coverage value or higher for each library type suggests that Roche kit tends to accumulate reads in low coverage regions (b). Mean percentage ± SD (n = 5) of on target bases for each library type. On target bases are referred to the number of aligned bases that map either on or near a bait within a 100 bp interval (c)