Fig. 1

Correlation of microRNAs and the expression of their target genes in OTSCC. The levels of miR-21 and miR-130b and the expression of HPGD, GPD1L, HLF and MGLL were extracted for 12 OTSCC and paired normal tissue samples from The Cancer Genome Atlas (TCGA) (a, d, g, j), assessed by qRT-PCR on 13 HNSCC cell lines (b, e, h, k), and on 13 oral cytology samples from OTSCC patients (c, f, i, l). The correlation of the miR-21 level with the expression of GPD1L (a, b, c), HLF (d, e, f), HPGD (g, h, i), and the correlation of miR-130b level with the expression of MGLL (j, k, l) were assessed, and the Pearson’s correlation coefficient (r) was calculated