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Fig. 4 | BMC Cancer

Fig. 4

From: Interleukin 12 shows a better curative effect on lung cancer than paclitaxel and cisplatin doublet chemotherapy

Fig. 4

NK cells are essential for the anti-tumor effects of IL-12. a Whole-body imaging of WT, Nfil3−/−, CD4−/− and CD8−/− tumor-bearing mice. Tumors detected in the Nfil3−/− group grew more robustly compared to the other groups whether IL-12 was administered or not. b The survival (Kaplan-Meier) curves of the treated animals are shown; No prolonged survival time was observed in the Nfil3−/− + IL-12 group as compared to the other groups. c The survival (Kaplan-Meier) curves of the treated animals are shown; A prolonged survival time was observed in the WT + IL-12 group as compared to other groups (log-rank test, P < 0.01)

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