Fig. 9
Bidirectional crosstalk between Gal-7+ tumors and their associated microenvironments. The expression of genes related to stromal cells, cancer associated fibroblasts, and immune cells results in an aggressive crosstalk that could potentially decide the fate of the tumor: proliferation and immune evasion, or immune destruction. The role of the common proteins in the Gal-7 network remains partially unknown. The color of the participant transcripts and proteins represents differential expression (up-regulation in red, down-regulation in blue)