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Table 2 BRCA1/2 mutation frequencies in patients with TNBC and non-TNBC

From: High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients

 

TNBC (N = 192)

Non-TNBC (N = 331)

P a

Mutation status

n (%)

n (%)

Carriers

73 (38.0)

52 (15.7)

< 0.0001 b

 BRCA1

71 (37.0)

34 (10.3)

< 0.0001 c

 BRCA2

2 (1.0)

18 (5.4)

NSd

Non-carriers

119 (62.0)

279 (84.3)

 
  1. P values marked in bold are statistically significant
  2. NS non-significant, TNBC triple-negative breast cancer
  3. aFisher’s exact test. bCarriers vs. non-carriers. cBRCA1 carriers vs. non-carriers
  4. dBRCA2 carriers vs. non-carriers
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BMC Cancer

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