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Table 2 BRCA1/2 mutation frequencies in patients with TNBC and non-TNBC

From: High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients

  TNBC (N = 192) Non-TNBC (N = 331) P a
Mutation status n (%) n (%)
Carriers 73 (38.0) 52 (15.7) < 0.0001 b
BRCA1 71 (37.0) 34 (10.3) < 0.0001 c
BRCA2 2 (1.0) 18 (5.4) NSd
Non-carriers 119 (62.0) 279 (84.3)  
  1. P values marked in bold are statistically significant
  2. NS non-significant, TNBC triple-negative breast cancer
  3. aFisher’s exact test. bCarriers vs. non-carriers. cBRCA1 carriers vs. non-carriers
  4. dBRCA2 carriers vs. non-carriers