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Table 3 Univariate and multivariate analyses of prognostic factors for OS of patients with resectable thoracic ESCC

From: The pretreatment Controlling Nutritional Status (CONUT) score is an independent prognostic factor in patients with resectable thoracic esophageal squamous cell carcinoma: results from a retrospective study

Variable 5-year OS (%) Univariate Multivariate
p value HR (95 % CI) p value
Total 60.7    
Age (years)   0.089 1.214 (0.753–1.956) 0.427
  < 65 68.5    
  ≥ 65 52.1    
Sex   0.004 0.276 (0.107–0.711) 0.008
 Male 56.0    
 Female 83.3    
BMI   0.479   
 <21.0 67.3    
 ≥21.0 54.2    
PS   <0.001 4.223 (2.155–8.274) <0.001
 0 64.6    
 1/2 8.3    
ASA   <0.001   <0.001
 1 81.2   1.000  
 2 59.6   1.184 (0.554–2.528) 0.663
 3 10.9   5.856 (2.102–16.310) 0.001
Location   0.941   
 Upper 58.6    
 Middle 60.7    
 Lower 62.3    
cTNM stage   0.001   0.015
 I 75.4   1.000  
 II 57.5   1.515 (0.850–2.698) 0.159
 III/IV 40.4   2.485 (1.338–4.615) 0.004
SCCA (ng/ml)   0.139   
 <2.0 61.2    
 ≥2.0 59.6    
CONUT score   <0.001 2.303 (1.191–4.455) 0.013
 High (≥3) 35.3    
 Low (≤2) 63.6    
PLR   0.025 1.213 (0.696–2.115) 0.496
 High (>193) 52.1    
 Low (≤193) 62.6    
NLR   0.018 1.194 (0.627–2.273) 0.589
 High (>3.612) 43.5    
 Low (≤3.612) 63.3    
GPS   0.001 1.021 (0.465–2.245) 0.958
 0 63.9    
 1/2 16.3    
Components of the CONUT score
 Albumin score   0.012 1.096 (0.479–2.511) 0.828
  0 61.4    
  2/4 0    
 TLC score   0.074 1.061 (0.518–2.171) 0.872
  0/1 62.6    
  2/3 47.6    
 TC score   0.015 1.481 (0.688–3.190) 0.316
  0/1 62.4    
  2/3 40.8    
  1. BMI body mass index, PS performance status, ASA American Society of Anesthesiology, TNM tumor-node-metastasis, SCCA squamous cell carcinoma antigen, CONUT Controlling Nutritional Status, PLR platelet to lymphocyte ratio, NLR neutrophil to lymphocyte ratio, GPS Glasgow Prognostic Score, TLC total lymphocyte count, TC total cholesterol
  2. The results of multivariate analyses of age, sex, PS, ASA, cTNM stage in this table are the results of analyses with CONUT score
  3. HRs and p values of PLR, NLR, GPS, Albumin score, TLC score, and TC score in this table are the results of respective multivariate analyses using variables with p < 0.1 on univariate analyses and each factor