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Table 2 Relationships between clinical characteristics and the CONUT

From: The pretreatment Controlling Nutritional Status (CONUT) score is an independent prognostic factor in patients with resectable thoracic esophageal squamous cell carcinoma: results from a retrospective study

Variables Total (n = 185) High-CONUT (n = 17) Low-CONUT (n = 168) p value
n % n % n %
Age (years)
  < 65 95 51.4 9 52.9 86 51.2  
  ≥ 65 90 48.6 8 47.1 82 48.8 0.891
Sex
 Male 152 82.2 17 100 135 80.4  
 Female 33 17.8 0 0 33 19.6 0.046*
BMI
  < 21.0 95 51.4 14 82.4 81 48.2  
  ≥ 21.0 90 48.6 3 17.6 87 51.8 0.010*
PS
 0 173 93.5 15 88.2 158 94.0  
 1/2 12 6.5 2 11.8 10 6.0 0.304*
ASA score
 1 34 18.4 2 11.8 32 19.0  
 2 140 75.7 14 82.4 126 75.0  
 3 11 5.9 1 5.9 10 6.0 0.757
Location
 Upper 27 14.6 3 17.6 24 14.3  
 Middle 106 57.3 8 47.1 98 58.3  
 Lower 52 28.1 6 35.3 46 27.4 0.668
cT stage
 cT1 73 39.5 4 23.5 69 41.1  
 cT2 44 23.8 5 29.4 39 23.2  
 cT3 68 36.8 8 47.1 60 35.7 0.369
cN stage
 Negative 128 69.2 10 58.8 118 70.2  
 Positive 57 30.8 7 41.2 50 29.8 0.331
Clinical TNM stage
 I 67 36.2 4 23.5 63 37.5  
 II 78 42.2 7 41.2 71 42.3  
 III/IV 40 21.6 6 35.3 34 20.2 0.293
SCCA (ng/ml)
 <2.0 148 80 12 70.6 136 81.0  
 ≥2.0 37 20 5 29.4 32 19.0 0.309
PLR        
 High (>193) 32 17.3 10 58.8 22 13.1  
 Low (≤193) 153 82.7 7 41.2 146 86.9 <0.001
NLR
 High (>3.612) 22 11.9 6 35.3 16 9.5  
 Low (≤3.612) 163 88.1 11 64.7 152 90.5 0.002
GPS
 0 171 92.4 12 70.6 159 94.6  
 1 13 7.0 4 23.5 9 5.4  
 2 1 0.5 1 5.9 0 0 <0.001
Components of the CONUT score
 Albumin score
  0 183 98.9 15 88.2 168 100  
  2/4 2 1.1 2 11.8 0 0 0.008*
 TLC score
  0 125 67.6 0 0 125 74.4  
  1 39 21.1 4 23.5 35 20.8  
  2/3 21 11.4 13 76.5 8 4.8 <0.001
 TC score
  0 113 61.1 2 11.8 111 66.1  
  1 58 31.4 9 52.9 49 29.2  
  2/3 14 7.6 6 35.3 8 4.8 <0.001
  1. CONUT Controlling Nutritional Status, BMI body mass index, PS performance status
  2. ASA American Society of Anesthesiology, TNM tumor-node-metastasis, SCCA squamous
  3. cell carcinoma antigen, PLR platelet to lymphocyte ratio, NLR neutrophil to lymphocyte ratio
  4. GPS Glasgow Prognostic Score, TLC total lymphocyte count, TC total cholesterol
  5. *Fisher’s exact test