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Table 2 Relationships between clinical characteristics and the CONUT

From: The pretreatment Controlling Nutritional Status (CONUT) score is an independent prognostic factor in patients with resectable thoracic esophageal squamous cell carcinoma: results from a retrospective study

Variables

Total (n = 185)

High-CONUT (n = 17)

Low-CONUT (n = 168)

p value

n

%

n

%

n

%

Age (years)

  < 65

95

51.4

9

52.9

86

51.2

 

  ≥ 65

90

48.6

8

47.1

82

48.8

0.891

Sex

 Male

152

82.2

17

100

135

80.4

 

 Female

33

17.8

0

0

33

19.6

0.046*

BMI

  < 21.0

95

51.4

14

82.4

81

48.2

 

  ≥ 21.0

90

48.6

3

17.6

87

51.8

0.010*

PS

 0

173

93.5

15

88.2

158

94.0

 

 1/2

12

6.5

2

11.8

10

6.0

0.304*

ASA score

 1

34

18.4

2

11.8

32

19.0

 

 2

140

75.7

14

82.4

126

75.0

 

 3

11

5.9

1

5.9

10

6.0

0.757

Location

 Upper

27

14.6

3

17.6

24

14.3

 

 Middle

106

57.3

8

47.1

98

58.3

 

 Lower

52

28.1

6

35.3

46

27.4

0.668

cT stage

 cT1

73

39.5

4

23.5

69

41.1

 

 cT2

44

23.8

5

29.4

39

23.2

 

 cT3

68

36.8

8

47.1

60

35.7

0.369

cN stage

 Negative

128

69.2

10

58.8

118

70.2

 

 Positive

57

30.8

7

41.2

50

29.8

0.331

Clinical TNM stage

 I

67

36.2

4

23.5

63

37.5

 

 II

78

42.2

7

41.2

71

42.3

 

 III/IV

40

21.6

6

35.3

34

20.2

0.293

SCCA (ng/ml)

 <2.0

148

80

12

70.6

136

81.0

 

 ≥2.0

37

20

5

29.4

32

19.0

0.309

PLR

       

 High (>193)

32

17.3

10

58.8

22

13.1

 

 Low (≤193)

153

82.7

7

41.2

146

86.9

<0.001

NLR

 High (>3.612)

22

11.9

6

35.3

16

9.5

 

 Low (≤3.612)

163

88.1

11

64.7

152

90.5

0.002

GPS

 0

171

92.4

12

70.6

159

94.6

 

 1

13

7.0

4

23.5

9

5.4

 

 2

1

0.5

1

5.9

0

0

<0.001

Components of the CONUT score

 Albumin score

  0

183

98.9

15

88.2

168

100

 

  2/4

2

1.1

2

11.8

0

0

0.008*

 TLC score

  0

125

67.6

0

0

125

74.4

 

  1

39

21.1

4

23.5

35

20.8

 

  2/3

21

11.4

13

76.5

8

4.8

<0.001

 TC score

  0

113

61.1

2

11.8

111

66.1

 

  1

58

31.4

9

52.9

49

29.2

 

  2/3

14

7.6

6

35.3

8

4.8

<0.001

  1. CONUT Controlling Nutritional Status, BMI body mass index, PS performance status
  2. ASA American Society of Anesthesiology, TNM tumor-node-metastasis, SCCA squamous
  3. cell carcinoma antigen, PLR platelet to lymphocyte ratio, NLR neutrophil to lymphocyte ratio
  4. GPS Glasgow Prognostic Score, TLC total lymphocyte count, TC total cholesterol
  5. *Fisher’s exact test