Skip to main content

Table 4 Relationship between length of non-steroideal anti-inflammatory drug consumption and breast cancer, according to women’s characteristics

From: Use of non-steroidal anti-inflammatory drugs and risk of breast cancer: The Spanish Multi-Case-control (MCC) study

Population

NSAID

No consumption

Consumption ≤5y

Consumption >5y

Controls/cases (n)

Controls/cases (n)

OR (95 % CI)

Controls/cases (n)

OR (95 % CI)

All women

NSAID (all)

1171/1111

484/445

0.81 (0.67–0.98)

255/180

0.64 (0.50–0.83)

Aspirin

1808/1653

79/70

0.99 (0.67–1.46)

23/13

0.65 (0.31–1.38)

Acetic acid derivatives

1754/1620

113/86

0.75 (0.53–1.06)

43/30

0.75 (0.42–1.32)

Propionic acid derivatives

1351/1232

380/364

0.86 (0.71–1.06)

179/140

0.73 (0.55–0.97)

NSAID others

1862/1697

33/35

1.47 (0.83–2.60)

15/4

-

Premenopausal

NSAID (all)

361/415

162/187

0.82 (0.59–1.13)

105/100

0.78 (0.52–1.17)

Aspirin

613/689

12/12

0.72 (0.27–1.95)

3/1

-

Acetic acid derivatives

600/664

21/27

0.68 (0.35–1.34)

7/11

1.02 (0.31–3.32)

Propionic acid derivatives

392/461

146/167

0.85 (0.61–1.19)

90/84

0.81 (0.52–1.25)

NSAID others

618/693

6/8

2.38 (0.63–9.00)

4/1

-

Postmenopausal

NSAID (all)

805/696

312/258

0.77 (0.61–0.98)

150/80

0.53 (0.38–0.75)

Aspirin

1181/964

66/58

1.08 (0.70–1.66)

20/12

0.74 (0.33–1.65)

Acetic acid derivatives

1143/956

88/59

0.76 (0.50–1.15)

36/19

0.61 (0.31–1.20)

Propionic acid derivatives

954/781

224/197

0.84 (0.64–1.09)

89/56

0.64 (0.43–0.95)

NSAID others

1229/1004

27/27

1.27 (0.66–2.42)

11/3

-

BMI <25

NSAID (all)

578/537

233/183

0.78 (0.58–1.04)

131/99

0.65 (0.45–0.94)

Aspirin

901/794

32/22

0.84 (0.43–1.63)

9/3

-

Acetic acid derivatives

883/783

44/22

0.40 (0.20–0.77)

15/14

1.16 (0.42–3.15)

Propionic acid derivatives

656/575

191/163

0.89 (0.66–1.21)

95/81

0.80 (0.52–1.22)

NSAID others

919/806

14/11

1.51 (0.56–4.06)

9/2

-

BMI >25

NSAID (all)

593/574

251/262

0.84 (0.65–1.08)

124/81

0.61 (0.43–0.86)

Aspirin

907/859

47/48

1.10 (0.68–1.80)

14/10

0.74 (0.30–1.82)

Acetic acid derivatives

871/837

69/64

0.94 (0.61–1.44)

28/16

0.54 (0.27–1.10)

Propionic acid derivatives

695/657

189/201

0.85 (0.64–1.12)

84/59

0.64 (0.43–0.95)

NSAID others

943/891

19/24

1.44 (0.71–2.95)

6/2

-

  1. OR Odds ratio adjusted for age, recruitment area, education level, tobacco smoking history, BMI family history of breast cancer, number of deliveries, age at first delivery, menarche age, and menopausal status. CI confidence interval
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us