Fig. 5From: Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine GliomaPre-treatment of DIPG cells with BI 6727 sensitizes them to ionizing radiation. a DIPG cells treated with IC30, IC50 and IC70 doses of BI 6727 for 24 h were then exposed to increasing doses of radiation. Cell proliferation was measured by MTS 5 days after radiation. Mean ± SEM shown b Calculated sensitizer enhancement ratios (SER) with 24-hour pre-treatment of BI 6727 at IC30, IC50 and IC70 dosesBack to article page