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Fig. 2 | BMC Cancer

Fig. 2

From: Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma

Fig. 2

Small molecule inhibition of PLK1 BI6727 suppresses in vitro DIPG cell proliferation and growth. a DIPG cells were treated for 72 h with increasing dose of the PLK1 small molecule inhibitor BI 6727. Cell proliferation was measured by MTS assay with the mean ± SEM shown. IC50 (in nM) values were calculated as shown. b DIPG cells were treated with increasing doses of BI 6727 for 72 h and total viable cell number was measured (± SEM) using Guava flow cytometry

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