Skip to main content

Table 9 Relative hazard for Nomo stages in derivation and external validation cohorts

From: Nomograms to predict survival after colorectal cancer resection without preoperative therapy

   Training cohort Validation cohort Test cohort
Nomo stages Cut-off Points HR 95 % CI P HR 95 % CI P HR 95 % CI P
Cancer-specific survival
 Nomo 1 ≤82.0 ref    ref    ref   
 Nomo 2 ≤106.2 1.86 1.48–2.35 <0.0001 2.40 1.19–4.84 0.0147 1.92 1.37–2.70 0.0002
 Nomo 3 ≤122.9 2.86 2.30–3.55 <0.0001 3.33 1.70–6.51 0.0004 3.38 2.48–4.62 <0.0001
 Nomo 4 ≤138.2 3.91 3.17–4.82 <0.0001 4.83 2.54–9.22 <0.0001 5.13 3.81–6.91 <0.0001
 Nomo 5 ≤153.0 5.58 4.55–6.84 <0.0001 6.60 3.50–12.42 <0.0001 7.87 5.89–10.51 <0.0001
 Nomo 6 ≤170.7 8.47 6.95–10.33 <0.0001 10.41 5.60–19.32 <0.0001 12.17 9.19–16.13 <0.0001
 Nomo 7 ≤192.2 12.46 10.25–15.14 <0.0001 16.23 8.84–29.81 <0.0001 18.39 13.91–24.3 <0.0001
 Nomo 8 ≤225.6 22.40 18.49–27.13 <0.0001 21.11 11.53–38.67 <0.0001 32.19 24.47–42.34 <0.0001
 Nomo 9 ≤272.1 40.47 33.46–48.94 <0.0001 42.87 23.56–78.00 <0.0001 65.32 49.79–85.68 <0.0001
 Nomo 10 272.1+ 83.31 68.9–100.73 <0.0001 86.07 47.39–156.31 <0.0001 127.46 97.2–167.12 <0.0001
Overall survival
 Nomo 1 ≤57.2 ref    ref    ref   
 Nomo 2 ≤70.0 2.16 1.83–2.56 <0.0001 1.96 1.19–3.22 0.0078 2.13 1.68–2.70 <0.0001
 Nomo 3 ≤80.8 3.04 2.59–3.58 <0.0001 2.63 1.64–4.21 0.0001 3.12 2.49–3.92 <0.0001
 Nomo 4 ≤90.7 4.76 4.08–5.56 <0.0001 4.28 2.73–6.71 <0.0001 5.55 4.48–6.87 <0.0001
 Nomo 5 ≤101.6 6.12 5.26–7.12 <0.0001 6.17 3.99–9.55 <0.0001 6.90 5.59–8.52 <0.0001
 Nomo 6 ≤114.2 9.01 7.76–10.45 <0.0001 8.41 5.47–12.92 <0.0001 11.11 9.06–13.63 <0.0001
 Nomo 7 ≤129.1 13.46 11.62–15.58 <0.0001 11.25 7.36–17.19 <0.0001 15.23 12.45–18.62 <0.0001
 Nomo 8 ≤147.1 18.68 16.15–21.61 <0.0001 16.81 11.04–25.61 <0.0001 24.23 19.85–29.57 <0.0001
 Nomo 9 ≤171.8 28.44 24.61–32.88 <0.0001 25.47 16.76–38.68 <0.0001 37.66 30.91–45.89 <0.0001
 Nomo 10 171.8+ 55.25 47.8–63.86 <0.0001 45.27 29.80–68.76 <0.0001 75.07 61.63–91.45 <0.0001
  1. HR hazard ratio, 95 % CI 95 % confident interval